Posted on September 09, 2018

Qatar University College of Pharmacy (QU-CPH) Qatari national MSc. student in pharmacy Asmaa Jafour Al-Mansouri recently defended her thesis titled “Assessment of treatment burden and its impact on quality of life in chronic kidney disease patients in Qatar: a mixed method study”.

The research study is the first to explore and describe treatment-related burden and quality of life among kidney failure patients -- both pre-dialysis and patients receiving dialysis -- in Qatar. It was conducted at Fahad Bin Jassim Kidney Center, a member of Hamad Medical Corporation (HMC). It is supervised by CPH Associate Professor of Clinical Pharmacy and Practice Dr. Ahmed Awaisu, CPH Professor of Social and Administrative Pharmacy Dr. Mohamed Izham Mohamed Ibrahim and Academic Director of Postgraduate Program-Taught at University of Auckland School of Pharmacy, Faculty of Medical and Health Sciences Dr. Nadir Kheir. 

The study found that a considerable proportion of patients suffered from treatment-related burden and deterioration in quality of life at a varying degree of seriousness. It further documented that marital status, educational level, employment status, co-morbidities such as type 2 diabetes, number of medications, and pill burden were all factors that significantly led to higher perceived treatment burden. Furthermore, the study indicated that higher treatment-related burden should be taken into account in the management strategies of kidney failure and the identified factors that increase treatment-related burden should be considered when designing health care interventions directed towards this patient population.

Asmaa Jafour Al-Mansouri noted that chronic kidney disease (CKD) in general and end-stage renal disease (ESRD) in particular contribute to high health and economic burden worldwide. She said: “In ESRD patients requiring dialysis, the number of prescribed medicines is typically very high. Management of CKD is associated with not only economic burden as a result of resources utilization and loss of productivity, it also leads to high treatment burden and impaired health-related quality of life (HR-QOL).” She added: “Our study confirmed the existence of treatment and medication-related burden among patients with CKD. We propose that pharmacists have an important role in decreasing medication-related burden associated among CKD patients. This will improve HR-QOL, save costs, and improve outcomes of care in patients with CKD in Qatar.”

Dr. Ahmed Awaisu said: “This project about treatment-related burden and its impact on quality of life in patients with kidney failure in Qatar is highly significant and relevant to Qatar National Health Strategy for the purpose of improving health outcomes. Asmaa Al-Mansouri did this project to gauge the current situation and propose future directions for minimizing this burden and improving outcomes. I am very proud that she did an outstanding job and has done a project that would potentially have an impact on practice, developing strategies for improving health care, and policy in Qatar. Asmaa is very enthusiastic about the project’s findings and how it can help local, regional, and international communities in improving care in chronic non-communicable diseases with high burden such as CKD. She aspires to contribute in future related projects.”